The full UFC 331 card has been revealed, and the September 19 event in Los Angeles is shaping up to be one of the year's biggest fight nights, anchored by a flyweight title rematch and a pivotal lightweight clash.

Van vs. Pantoja II: Unfinished Business

Joshua Van puts his UFC flyweight championship on the line against Alexandre Pantoja in the night's main event — a rematch that was made necessary by one of the more unfortunate endings in recent memory. During their first meeting in 2025, Pantoja's arm gave out after he landed awkwardly in the opening round, abruptly ending what had been a dominant title reign. The injury forced a stoppage before either man could truly settle the question of who the better fighter is.

Van wasted no time establishing himself as a legitimate champion during Pantoja's recovery. The new titleholder delivered what many are calling a Fight of the Year contender against Tatsuro Taira in May, successfully defending the belt in spectacular fashion. Now, with Pantoja fully healthy and hungry, Van gets his chance to silence any remaining doubters about the legitimacy of his reign.

Tsarukyan and Ruffy Collide at 155

The co-main event brings together two lightweights with serious title aspirations, as Arman Tsarukyan squares off with Mauricio Ruffy in a scheduled five-round bout. Both men are chasing a shot at current champion Justin Gaethje, making this a pivotal matchup at 155 pounds.

Tsarukyan enters riding a five-fight winning streak that includes notable victories over Charles Oliveira, Beneil Dariush, and Dan Hooker — a run that has cemented him as the division's premier contender. He spent much of the past year competing in RAF, wrestling on a near-monthly basis, and now returns to the Octagon looking to keep his momentum rolling.

Ruffy, meanwhile, arrives with serious confidence after a dominant showing at the UFC White House card, where he dismantled Michael Chandler in stunning fashion. That performance extended his winning streak to three consecutive victories, and he'll look to make it four against one of the toughest opponents of his career.

Full Card Taking Shape

Beyond the two marquee bouts, the remainder of the UFC 331 lineup has also been announced, though the complete bout order is yet to be determined. The event takes place September 19 in Los Angeles, and with the main card already stacked, fight fans have plenty of reason to circle the date on their calendars.